PROTAC MPS1 degrader 1 (Compound 19) is a potent degrader of monopolar spindle 1 (Mps1, TTK), AURKA and AURKB, with DC50s of 17.7, 108.7 and 570.3 nM, respectively. PROTAC MPS1 degrader 1 can be used for the research of acute myeloid leukemia. (Pink: ligand for target protein (HY-168542), Black: linker (HY-W141926), Blue: ligand for E3 ligase (HY-10984)[1].
Molecular Weight:
818.88
Purity:
93.94
Formula:
C41H46N12O7
Target:
Aurora Kinase,Mps1,PROTACs
Application Notes:
MCE Product type: Reference compound
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