YJ1206 is an orally active selective CDK12/CDK13 PROTAC degrader. YJ1206 induces DNA damage and genomic instability, activates the AKT pathway, and triggers apoptosis. YJ1206 reduces tumor cell viability, inhibits tumor growth, and attenuates tumor cell dissemination. YJ1206 is applicable to research related to prostate cancer and high-grade serous tubo-ovarian cancer[1][2].
Molecular Weight:
894.01
Purity:
96.92
CAS Number:
[3053716-98-3]
Formula:
C49H52FN11O5
Target:
Akt,Apoptosis,CDK,mTOR,PROTACs
Application Notes:
MCE Product type: Reference compound
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