MGD-4 is an orally active, Cereblon (CRBN)-dependent IKAROS protein degrader that degrades IKZF1 (DC50=67.2 nM), IKZF2 (DC50=918.2 nM), and IKZF3 (DC50=95.8 nM) in a dose-dependent manner. MGD-4 effectively inhibits the growth of multiple myeloma[1].
Molecular Weight:
288.30
Purity:
95.86
CAS Number:
[2991817-99-1]
Formula:
C14H16N4O3
Target:
IKZF Family
Application Notes:
MCE Product type: Reference compound1
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