MGD-28 is a potent, orally active, Cereblon (CRBN)-dependent IKAROS protein degrader that degrades IKZF1 (DC50=3.8 nM), IKZF2 (DC50=56.3 nM), and IKZF3 (DC50=7.1 nM) in a dose-dependent manner. In addition, MGD-4 also degrades CK1alpha (DC50=7.8 nM). MGD-28 has antiproliferative activity and can be used in multiple myeloma research[1].
Molecular Weight:
595.67
Purity:
99.73
CAS Number:
[2991818-13-2]
Formula:
C33H34FN7O3
Target:
Casein Kinase,IKZF Family
Application Notes:
MCE Product type: Reference compound
* VAT and and shipping costs not included. Errors and price changes excepted
