DNA Gyrase/DHFR-IN-1 is a dual inhibitor of bacterial DNA gyrase and DHFR, with IC50s of 182 µM and 3.90 µM for E. coli DNA gyrase and DHFR respectively. DNA Gyrase/DHFR-IN-1 has bactericidal and antifungal activity[1].
Molecular Weight:
392.45
Formula:
C25H20N4O
Target:
Bacterial,Dihydrofolate reductase (DHFR) ,Fungal
Application Notes:
MCE Product type: Reference compound
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