WEE1 degrader 1 (Compound 10) is a CRBN-dependent molecular glue degrader of WEE1 and casein kinase 1alpha (CK1alpha) with sub-2 nM DC50 values for both targets. WEE1 degrader 1 can be used for the research of acute lymphoblastic leukemia, acute monocytic leukemia, acute promyelocytic leukemia, colorectal adenocarcinoma, diffuse large b cell lymphoma[1].
Molecular Weight:
509.60
Purity:
99.74
CAS Number:
[3090685-34-7]
Formula:
C30H31N5O3
Target:
Wee1
Application Notes:
MCE Product type: Reference compound
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