TLR4/NF-kappaB-IN-1 (Compound 7x) is an orally available inhibitor that specifically targets the TLR4/NF-kappaB signaling pathway, offering anti-inflammatory effects and the ability to cross the blood-brain barrier. TLR4/NF-kappaB-IN-1 can reduce acute neuroinflammation in mice caused by LPS (HY-D1056) and downregulate the expression of TLR4, P-NF-kappaB and P-IkappaB-alpha proteins[1].
Molecular Weight:
374.37
Purity:
99.92
CAS Number:
[3050836-94-4]
Formula:
C20H15FN6O
Target:
IKK,NF-kappaB,Toll-like Receptor (TLR)
Application Notes:
MCE Product type: Reference compound
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