P-gp inhibitor 27 (Compound D2) is an inhibitor for P-glycoprotein (P-gp), that downregulates the expression of P-gp and MRP1, increases the Rh123 accumulation in A2780/T cell, and reverses multidrug resistance to Paclitaxel (HY-B0015) (EC50 is 88 nM) and Cisplatin (HY-17394)[1].
Molecular Weight:
431.48
Formula:
C25H25N3O4
Target:
P-glycoprotein
Application Notes:
MCE Product type: Reference compound
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