LZ-007 is an agonist for farnesoid X receptor (FXR) with an EC50 of 51 nM measuring by TR-FRET assay, or an EC50 of 76 nM in HepG2 cell. LZ-007 exhibits good pharmacokinetic characheristics in SD rats. LZ-007 ameliorates western diet and CCl4 (HY-Y0298)-induced mice metabolic dysfunction-associated steatohepatitis[1]
Molecular Weight:
518.52
CAS Number:
[2920000-23-1]
Formula:
C27H29F3N2O5
Target:
FXR
Application Notes:
MCE Product type: Reference compound
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