NEK7-IN-2 (compound 23) is a potent inhibitor of NLRP3-NEK7 interaction. NEK7-IN-2 can enhance the thermal stability of NEK7 and regulatie NLRP3 inflammasome assembly. NEK7-IN-2 inhibits IL-1beta releases[1].
Molecular Weight:
544.54
Formula:
C27H28F4N6O2
Target:
NEKs,NOD-like Receptor (NLR)
Application Notes:
MCE Product type: Reference compound
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