O-Acetylsalicylhydroxamic acid is an acetylation inhibitor of prostaglandin H2 synthase that can suppress PGE2 synthesis in the body and block the cyclooxygenase activity of PGHS in vitro. O-Acetylsalicylhydroxamic acid requires the presence of the active site residue Ser-529 to act on human PGHS-1, the S529A mutant is resistant to the inactivation effects of this inhibitor[1].
Molecular Weight:
195.17
CAS Number:
[199854-00-7]
Formula:
C9H9NO4
Target:
COX,Prostaglandin Receptor
Application Notes:
MCE Product type: Reference compound
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