Tamoxifen-PEG-Clozapine is an estrogen receptor alpha (ERalpha) PROTAC degrader. Tamoxifen-PEG-Clozapine degrades ERalpha via a ubiquitin-proteasome system that uses the ubiquitin protein ligase E3 component N-recognin 5. Tamoxifen-PEG-Clozapine can be used for the research of cancer[1]. (Pink: ERalpha inhibitor (HY-W271653), Black: linker (HY-168870), Blue: CRBN Ligand (HY-G0021))
Molecular Weight:
943.57
Formula:
C54H63ClN6O7
Target:
Estrogen Receptor/ERR,PROTACs
Application Notes:
MCE Product type: Reference compound
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