TrxR1-IN-2 (Compound 6a) is a TrxR1 inhibitor that covalently binds to the Cys475 and Sec498 sites of TrxR1, thereby inhibiting TrxR1 activity and leading to redox homeostasis disruption, which triggers apoptosis and ferroptosis[1].
Molecular Weight:
361.39
Formula:
C19H23NO6
Target:
Apoptosis,Ferroptosis,TrxR
Application Notes:
MCE Product type: Reference compound
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