EP652 is a METTL3 inhibitor and antitumor agent with IC50 values of 2 nM, FTO, and possesses favorable pharmacokinetic parameters. EP652 reduces intracellular N6-methyladenosine (m6A) levels in mRNA. EP652 inhibits tumor growth and progression of both hematologic malignancies and solid tumors. EP652 can be used for the research of acute myeloid leukemia, ovarian cancer, non-small cell lung cancer, and hypopharyngeal squamous cell carcinoma[1].
Molecular Weight:
462.59
CAS Number:
[3050819-22-9]
Formula:
C25H34N8O
Target:
METTL3
Application Notes:
MCE Product type: Reference compound
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