AV457 is a potent and selective mTOR inhibitor with an IC50 value of 0.54 µM. AV457 inhibits cyst growth in polycystic kidney disease (PKD) organoids. AV457 decreases the protein expression of P-s6, P-p70s6 and dont decreases the protein expression of P-AKT[1].
Molecular Weight:
1065.36
CAS Number:
[2713387-11-0]
Formula:
C55H88N2O16S
Target:
mTOR
Application Notes:
MCE Product type: Reference compound
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