Jun13296 is an orally active quinoline SARS-CoV-2 papain-like protease inhibitor (IC50 = 0.13 µM, Ki = 8.8 nM). Jun13296 exhibits potent inhibition against SARS-CoV-2 variants and Nirmatrelvir (HY-138687)-resistant mutants. Jun13296 improves lung viral titers, and prevents lung tissue damage in a SARS-CoV-2 infection model[1].
Molecular Weight:
494.63
CAS Number:
[3063566-68-4]
Formula:
C30H34N6O
Target:
SARS-CoV,Virus Protease
Application Notes:
MCE Product type: Reference compound
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