9-AMN is the inhibitor for SARS-CoV-2 papain-like protease (SARS-CoV-2 PLpro), inhibits its deubiquitination (DUB) activity and protease activity with IC50 of 4.55 µM and 4.15 µM. 9-AMN inhibits the SARS-CoV variants Delta and Omicron replication in Calu-3 cell with IC50 of 1.04 µM and 2.35 µM[1].
Molecular Weight:
472.49
Formula:
C23H28N4O7
Target:
SARS-CoV,Virus Protease
Application Notes:
MCE Product type: Reference compound
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