KRASG12C IN-16 (Compound SK-17) is a selective, covalent and an orally active KRASG12C inhibitor. KRASG12C IN-16 induces Apoptosis. KRASG12C IN-16 effectively prevents the activation of MAPK and PI3K/mTOR signaling pathways. KRASG12C IN-16 displays anti-tumor activity against pancreatic cancer[1].
Molecular Weight:
551.08
Formula:
C28H35ClN8O2
Target:
Apoptosis,mTOR,p38 MAPK,PI3K,Ras
Application Notes:
MCE Product type: Reference compound
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