Wnt/beta-catenin activator 1 (Compound 5m) is the orally active activator for Wnt/beta-catenin signaling pathway, that arrests cell cycle at G1 phase, inhibits early proliferation of adipocytes, and inhibits adipogenesis in cell 3T3-L1 with an IC50 of 330 nM. Wnt/beta-catenin activator 1 exhibits anti-adipogenic and anti-dyslipidemic activities in high-fat diet fed Syrian golden hamster model[1].
Molecular Weight:
382.43
Formula:
C26H19FO2
Target:
Wnt,beta-catenin
Application Notes:
MCE Product type: Reference compound
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