NQO2-IN-1 (Compound 20b) is the inhibitor for quinone oxidoreductase (NQO) that inhibits NQO2 with an IC50 of 95 nM. NQO2-IN-1 overcomes the resistance of NSCLC cells to tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) by induction of ROS and apoptosis[1].
Molecular Weight:
310.35
Purity:
98.02
CAS Number:
[2920687-14-3]
Formula:
C18H18N2O3
Target:
Apoptosis,Reactive Oxygen Species (ROS)
Application Notes:
MCE Product type: Reference compound
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