Anti-inflammatory agent 95 (Compound 2e) is an anti-inflammatory agent that exhibits the most potent anti-inflammatory activity in LPS (HY-D1056)-induced RAW 264.7 mouse macrophages. It significantly inhibits the production of NO, with an IC50 of 8.8 µM, and reduces the secretion of TNF-alpha and IL-1beta, with inhibition rates reaching 60% and over 90%, respectively, at a concentration of 100 µM. Anti-inflammatory agent 95 holds promise for research in the field of inflammatory diseases[1].
Molecular Weight:
291.34
Formula:
C16H21NO4
Target:
Interleukin Related,NO Synthase,TNF Receptor
Application Notes:
MCE Product type: Reference compound
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