ROS inducer 8 (Compound 11g) is the inhibitor for glutathione (GSH), that induces the ROS accumulation in Enterococcus faecalis, thereby exhibiting antibacterial activity. ROS inducer 8 disrupts the biofilm, inhibits S. aureus and E. faecalis with MIC of 8 µg/mL and 2 µg/mL, exhibits post-antibiotic effect. ROS inducer 8 exhibits low hemolytic toxicity to sheep erythrocytes (HC50 > 1280 µg/mL)[1].
Molecular Weight:
542.56
Formula:
C26H31FN6O6
Target:
Bacterial,Reactive Oxygen Species (ROS)
Application Notes:
MCE Product type: Reference compound
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