ZJY-54 is an orally active dual-target inhibitor of EGFR/LSD1, with IC50 values of 3.8 nM and 0.6 µM, respectively. ZJY-54 can inhibit the proliferation of non-small cell lung cancer cells, induce the accumulation of H3K4me2 and H3K9me2, and inhibit the phosphorylation of the EGFR signaling pathway. ZJY-54 has anti-tumor activity[1].
Molecular Weight:
514.64
CAS Number:
[3091379-82-4]
Formula:
C29H30D3N7O2
Target:
EGFR,Histone Demethylase
Application Notes:
MCE Product type: Isotope-Labeled Compounds
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