AA-BR-157

Product Overview

• Article Name: AA-BR-157
• Biozol Catalog Number: MCE-HY-168969
• Supplier Catalog Number: HY-168969
• Alternative Catalog Number: MCE-HY-168969-10MG,MCE-HY-168969-5MG,MCE-HY-168969-1MG
• Manufacturer: MedchemExpress
• Category: Biochemikalien

Product Description

AA-BR-157 is a PROTAC degrader for metallothionein 2A (MT2A) with a DC50 of 190 nM. AA-BR-157 downregulates the cytoskeleton and cell motility regulating protein DIAPH3, inhibits the migration of MDA-MB-231 and U-87 MG. AA-BR-157 regulates the zinc homeostasis in MDA-MB-231[1]. (Pink: ligand for target protein MT2A ligand 1 (HY-168970), Black: linker (HY-119429), Blue: ligand for VHL E3 ligase (HY-125845))

Product Properties

• Molecular Weight: 1095.33
• Purity: 96.47
• Formula: C56H70N8O11S2
• Target: PROTACs

Application Notes

• Application Notes: MCE Product type: Reference compound