Famlasertib is a potent, brain-penetrant MAP4K inhibitor with IC50s value of 0.3 nM, 23.7 nM, and 44.7 nM for HGK (MAP4K4), MLK3, and MLK1, respectively. Famlasertib shows motor neuron protection and anti-inflammatory properties. Famlasertib can be used for the study of amyotrophic lateral sclerosis (ALS)[1][2].
Molecular Weight:
446.97
Purity:
99.94
CAS Number:
[2375591-69-6]
Formula:
C26H27ClN4O
Target:
MAP4K,Mixed Lineage Kinase
Application Notes:
MCE Product type: Reference compound
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