Ontunisertib (AGMB-129) is an orally active and selective gastrointestinal-restricted ALK5 (TGFbetaR1) inhibitor. Ontunisertib blocks signalling of the pro-fibrotic TGFbeta pathway. Ontunisertib can be used for the research of fibrostenotic Crohns disease[1][2].
Molecular Weight:
469.49
Purity:
99.95
CAS Number:
[2647949-48-0]
Formula:
C27H21F2N5O
Target:
TGF-beta Receptor
Application Notes:
MCE Product type: Reference compound
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