UNC6535 TFA is a covalent ligand targeting the triple Tudor domain (3TD) of SETDB1. UNC6535 TFA reversibly binds to the aromatic cages of both TD2 and TD3 within SETDB1 3TD simultaneously, weakly inhibits the methyltransferase activity of SETDB1, and displaces the H3K9Me2K14Ac peptide from SETDB1 3TD[1].
Molecular Weight:
688.70
Purity:
99.0600
Formula:
C29H46F6N6O6
Target:
Histone Methyltransferase
Application Notes:
MCE Product type: Reference compound
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