KL-465 is a PROTAC degrader for MAGE-A3, that degrades MAGE-A3 with a DC50 of 2 µM in HeLa cell. KL-465 inhibits viability of MAGE-A3 positive cancer cell HCT116, A375 and HeLa. (Blue: Ligand for E3 ligase (HY-151227), Black: Linker (HY-W679862), Pink: Ligand for target protein (HY-169087))[1]
Molecular Weight:
1021.19
CAS Number:
[3057446-82-6]
Formula:
C56H60N8O9S
Target:
PROTACs
Application Notes:
MCE Product type: Reference compound
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