PF-07957472 (Compound 4) is an orally active and selective SARS-CoV-2 papain-like protease (PLpro) inhibitor, with a Ki of 2 nM against SARS-CoV-2 PLpro. PF-07957472 reduces SARS-CoV-2 viral titers in the lungs of infected mice and inhibits SARS-CoV-2-induced cytopathic effects in cells. PF-07957472 can be used for the research of COVID-19[1].
Molecular Weight:
480.60
Purity:
99.13
CAS Number:
[3041047-51-9]
Formula:
C29H32N6O
Target:
SARS-CoV,Virus Protease
Application Notes:
MCE Product type: Reference compound
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