PF-07957472 (Compound 4) is an orally active SARS-CoV-2 papain-like protease (PLpro) inhibitor. PF-07957472 shows cytopathic effect in SARS-CoV-2 infected NHBE cells (EC50 = 13.9 nM). PF-07957472 shows antiviral effect in a mouse-adapted model of COVID-19 infection model[1].
Molecular Weight:
480.60
Purity:
99.13
CAS Number:
[3041047-51-9]
Formula:
C29H32N6O
Target:
SARS-CoV,Virus Protease
Application Notes:
MCE Product type: Reference compound
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