ALKBH1-IN-4 prodrug (Compound 29E) is a prodrug of a DNA N6-methyladenine demethylase ALKBH1 inhibitor that significantly increases the abundance of 6mA in cells and upregulates the AMPK signaling pathway, thereby inhibiting the viability of gastric cancer cells. ALKBH1-IN-4 prodrug exhibits excellent cellular activity and favorable metabolic exposure in vivo, and holds promise for research in gastric cancer[1].
Molecular Weight:
354.36
Purity:
99.15
CAS Number:
[3056005-98-9]
Formula:
C18H18N4O4
Target:
AMPK
Application Notes:
MCE Product type: Reference compound
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