I194496 is a potent cystathionine gamma-lyase (CSE) inhibitor, with an IC50 of 0.79 mM. I194496 can inhibit the growth of human TNBC cells via the dual targeting PI3K/Akt and Ras/Raf/ERK pathway and suppress the metastasis of human TNBC cells via down-regulating Anxa2/STAT3 and VEGF/FAK/Paxillin signaling pathways[1].
Molecular Weight:
579.57
Purity:
98.52
CAS Number:
[445238-07-3]
Formula:
C28H23F2N5O5S
Target:
Akt,Annexin A,ERK,FAK,PI3K,Raf,Ras,STAT,VEGFR
Application Notes:
MCE Product type: Reference compound1
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