PDIC-NN (PDIC-NS free base) is a STING activator with anticancer activity. PDIC-NN promotes the content and biostability of endogenous cyclic dinucleotides (CDNs). PDIC-NN triggers ROS burst and causes serious damage to mitochondria. PDIC-NN induces cell apoptosis and inhibits DNA replication. PDIC-NN activates cGAS-STING signaling pathway, enhances the immunogenicity of tumor cells and activates a robust innate immune response[1][2].
Molecular Weight:
670.37
CAS Number:
[932740-48-2]
Formula:
C32H24Cl4N4O4
Target:
Apoptosis,Reactive Oxygen Species (ROS),STING
Application Notes:
MCE Product type: Reference compound
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