CK-666 is a cell-permeable actin-related protein Arp2/3 complex inhibitor (IC50=12 µM). CK-666 binds to Arp2/3 complex, stabilizes the inactive state of the complex, blocking movement of the Arp2 and Arp3 subunits into the activated filament-like (short pitch) conformation[1][2].
Molecular Weight:
296.34
Purity:
99.95
CAS Number:
[442633-00-3]
Formula:
C18H17FN2O
Target:
Arp2/3 Complex,HIV
Application Notes:
MCE Product type: Reference compound1
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