Latrunculin A (LAT-A), found in the red sea sponge Latrunculia magnifica, is a G-actin polymerization inhibitor. Latrunculin A binds to actin monomers and inhibits polymerization of actin with Kds of 0.1, 0.4, 4.7 µM and 0.19 µM for ATP-actin, ADP-Pi-actin, ADP-actin and G-actin, respectively. Latrunculin A has effective anti-metastatic properties for cancer research. Latrunculin A blocks cell migration[1][2][3][4][5][6].
Molecular Weight:
421.55
Purity:
98.9
CAS Number:
[76343-93-6]
Formula:
C22H31NO5S
Target:
Arp2/3 Complex
Application Notes:
Natural Products
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