BIO-2007817 is a Parkin positive allosteric modulators (PAMs). BIO-2007817 enhances the activity of wildtype Parkin. BIO-2007817 stimulates Parkin (an E3 ligase)autoubiquitination and induces the appearance of monoubiquitinated forms of Miro1 (EC50: 0.17 µM)[1].
Molecular Weight:
552.67
Purity:
99.35
Formula:
C32H36N6O3
Target:
E1/E2/E3 Enzyme,PINK1/Parkin
Application Notes:
Reference compound
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