CSI86 is a MYC-targeting PROTAC degrader with antiproliferative activity (IC50: 13-18 µM)[1]. CSI86 is composed of MYC inhibitor (red part) CSI118 TFA (HY-169379), E3 ligase ligand (blue part) VH032 (HY-120217), and PROTAC linker (black part) Succinic anhydride (HY-79369). The conjugate composed of E3 ligase ligand and linker is (S,R,S)-CO-C2-acid (HY-131866).
Molecular Weight:
1040.00
Formula:
C48H50F9N7O7S
Target:
c-Myc,PROTACs
Application Notes:
Reference compound
* VAT and and shipping costs not included. Errors and price changes excepted
