YT 6-2-PEG3-C2-NH2 is the p62/SQSTM1 targeting, autophagy-targeting ligand-linker conjugate of AUTOTAC ATC-324 (HY-169385), which is an bivalent AR (Androgen Receptor) degrader. ATC-324 can reduce nuclear AR levels and downregulate target gene expression of AR and AR-v7, and also has a degradation effect on common AR mutants in PCa[1].
Molecular Weight:
634.71
Purity:
99.50
Formula:
C33H44F2N2O8
Target:
AUTOTACs
Application Notes:
Reference compound
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