VEGFR-2-IN-59 (Compound 3h) is an inhibitor for VEGFR2 with an IC50 of 3.73 µM. VEGFR-2-IN-59 exhibits cytotoxicity in cancer cell A549, HT-29, A375, MCF7 and NHDF with IC50 of 20.91, 19.70, 9.63, 17.43 and 20.71 µM. VEGFR-2-IN-59 inhibits formation of tubular structure and exhibits anti-angiogenic property[1].
Molecular Weight:
396.40
Formula:
C19H20N6O4
Target:
VEGFR
Application Notes:
MCE Product type: Reference compound
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