AKT-IN-25 (Compound 14a) is an inhibitor for Akt, that inhibits the phosphorylation of Akt, and thereby inhibits the PI3K/Akt/mTOR signaling pathway. AKT-IN-25 arrests the cell cycle at G1 phase, inhibits the cell migration of PANC-1, and inhibits the proliferation of cancer cells PANC-1, PATU-T, and SUIT-2 with IC50s of 3.05, 1.32, and 3.85 µM, respectively[1].
Molecular Weight:
256.30
CAS Number:
[1619929-59-7]
Formula:
C14H16N4O
Target:
Akt
Application Notes:
MCE Product type: Reference compound
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