Tubulin polymerization-IN-71 (Compound 4k) is an inhibitor for tubulin polymerization with an IC50 of 3.06 µM. Tubulin polymerization-IN-71 inhibits the proliferation of cancer cell MG-63 and U2OS with IC50 of 0.08-0.14 µM. Tubulin polymerization-IN-71 arrests the cell cycle at G2/M phase, and induces apoptosis in MG-63[1].
Molecular Weight:
485.46
Formula:
C25H24FNO8
Target:
Apoptosis,Microtubule/Tubulin
Application Notes:
MCE Product type: Reference compound
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