LTB is a prodrug formed by coupling glycolysis inhibitor (Lonidamine (HY-B0486)) with PD1/PDL1 blocker (BMS-1 (HY-19991)) by thioketal linkage. LTB can further encapsulate photosensitizer chlorine e6 (Ce6) (HY-13594) to construct a co-delivery photodynamic nanoplatform (LTB-6 NPs) by self-assembly[1].
Molecular Weight:
985.09
Formula:
C53H59Cl2N3O7S2
Target:
PD-1/PD-L1
Application Notes:
MCE Product type: Reference compound
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