Topoisomerase I/II inhibitor 8, CAS [[355400-87-2]] Preis auf Anfrage
Biozol Catalog Number:
MCE-HY-169509
Supplier Catalog Number:
HY-169509
Alternative Catalog Number:
MCE-HY-169509-1UNIT
Manufacturer:
MedchemExpress
Category:
Biochemikalien
Topoisomerase I/II Inhibitor 8 (Compound Ru7) is a dual catalytic inhibitor of Topoisomerase I/II, capable of inducing DNA damage and PARP-1 activation, which subsequently leads to the activation of RIPK1, RIPK3, and MLKL, ultimately triggering necroptosis. Topoisomerase I/II Inhibitor 8 demonstrates remarkable anticancer activity by effectively targeting the nuclei of cancer cells and inducing cell death through necroptosis, showing great clinical potential in circumventing drug resistance in cancer treatment[1].
