SBI-0206965 is a potent, selective and cell permeable autophagy kinase ULK1 inhibitor with IC50s of 108 nM for ULK1 kinase and 711 nM for the highly related kinase ULK2. SBI-0206965 is also an AMPK inhibitor that can paradoxically increase Thr172 phosphorylation[1][2][3].
Molecular Weight:
489.32
Purity:
99.92
CAS Number:
[1884220-36-3]
Formula:
C21H21BrN4O5
Target:
AMPK,Apoptosis,Autophagy,ULK
Application Notes:
MCE Product type: Reference compound
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