SB-332235 is a potent, orally active nonpeptide CXCR2 antagonist, with an IC50 of 7.7 nM. SB-332235 displays 285-fold selectivity for CXCR2 over CXCR1. SB-332235 inhibits acute and chronic models of arthritis in the rabbit. SB-332235 inhibits viability of AML cells[1][2].
Molecular Weight:
410.66
Purity:
98.7
CAS Number:
[276702-15-9]
Formula:
C13H10Cl3N3O4S
Target:
CXCR
Application Notes:
MCE Product type: Reference compound
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