Ferroptosis-IN-16 (Compound 13l) is a specific inhibitor for ferroptosis with an EC50 of 0.7 nM and 0.9 nM in ES-2 cell and LX-2 cell. Ferroptosis-IN-16 ameliorates Acetaminophen (HY-66005)-induced acute liver injury in mouse model, and exhibits good metabolic stability in mouse liver microsomes[1].
Molecular Weight:
421.49
Formula:
C26H23N5O
Target:
Ferroptosis
Application Notes:
MCE Product type: Reference compound1
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