ZG297 is an agonist for Staphylococcus aureus ClpP (SaClpP ) with an EC50 of 0.26 µM. ZG297 degrades SaFtsZ, inhibits the bacterial cell division, thereby exhibiting antistaphylococcal activity, that inhibits S. aureus 8325-4 strains and MRSA strains with MIC of 0.063-256 µg/mL. ZG297 exhibits anti-infectious efficacy in mouse models[1].
Molecular Weight:
568.63
CAS Number:
[2999673-52-6]
Formula:
C31H35F3N4O3
Target:
Antibiotic,Bacterial
Application Notes:
MCE Product type: Reference compound1
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