Darunavir (TMC114), an orally active next generation HIV protease inhibitor, has a similar antiviral activity against the mutant and the wild-type viruses. Darunavir (TMC114) is potent against laboratory HIV-1 strains and primary clinical isolates (IC50 = 0.003 µM, IC90 = 0.009 µM) with minimal cytotoxicity[1][2].
Molecular Weight:
547.66
Purity:
99.91
CAS Number:
[206361-99-1]
Formula:
C27H37N3O7S
Target:
HIV,HIV Protease
Application Notes:
MCE Product type: Reference compound
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