Bfl-1-IN-6 (Compound 20) is an orally active inhibitor for Bcl-2 related protein A1 (BFL1) with an IC50 of 19 nM. Bfl-1-IN-6 stabilizes BFL1 protein, activates cleaved caspase 3, and exhibits antitumor efficacy in mouse models[1].
Molecular Weight:
402.89
Formula:
C22H24ClFN2O2
Target:
Bcl-2 Family,Caspase
Application Notes:
MCE Product type: Reference compound1
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