PKMYT1-IN-8 (Compound 137) is the inhibitor for PKMYT1 with an IC50 of 9 nM. PKMYT1-IN-8 inhibits EPHB3, EPHA1, KIT, EPHB1, EPHA2, EPHA3, and EPHB2with IC50s of 1.79, 3.17, 4.29, 6.32, 6.83, 8.10, and 10.9 µM, respectively. PKMYT1-IN-8 inhibits the proliferation of cancer cell OVCAR3 with GI50 of 2.02 µM[1].
Molecular Weight:
379.34
Purity:
99.31
Formula:
C17H16F3N5O2
Target:
Ephrin Receptor,Wee1
Application Notes:
MCE Product type: Reference compound
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