NOX4-IN-1 (Compound 14m) is the inhibitor for NADPH oxidase 4 (NOX4), and blocks the generation of ROS. NOX4-IN-1 inhibits TGF-beta1/Smad signaling pathway, decreases the expression of fibrosis-related proteins. NOX4-IN-1 inhibits the cell migration of NRK-49F[1].
Molecular Weight:
453.88
Formula:
C26H16ClN3O3
Target:
NADPH Oxidase,Reactive Oxygen Species (ROS),TGF-beta/Smad
Application Notes:
MCE Product type: Reference compound
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